Chemotherapy-induced peripheral neuropathy (CIPN) affects many people who have undergone chemotherapy treatment. This treatment and medication-resistant nerve pain can be severely debilitating.

Michele had undergone chemo in 2012. Since that time, she suffered from CIPN, even though she is cancer-free today, thankfully. After trying traditional pain management options–pain medications and procedures to lessen the nerve pain–and achieving no sustained pain relief–she traveled from Connecticut to New Jersey to try Calmare scrambler therapy.
The US FDA cleared scrambler therapy for CIPN treatment in 2009. Since then, several clinical trials from the nation’s most prestigious medical research hospitals have also found that scrambler therapy has been markedly successful in treating post-chemotherapy nerve pain.

The Foundation for Peripheral Neuropathy reported:
“Scrambler Therapy (marketed as Calmare™ Therapy in the United States) is a new type of pain relief that uses a rapidly changing electrical impulse to send a “non-pain” signal along the same pain fibers that are sending the “pain” stimulus. We got interested in Scrambler Therapy because we thought it MIGHT help CIPN patients, and Scrambler Therapy appeared to be non-toxic. It had been cleared for safety by the FDA in 2009.
We treated 16 patients with refractory CIPN (present for at least 6 months and refractory to medications), the group had a 60% reduction in their CIPN pain – in 10 days of treatment.
Of the 16 patients we treated, essentially all reported some benefit,
including 4 whose pain resolved to “0.”
Function improved in most patients including less interference with walking and sleeping, for at least 3 months.”
Read more scrambler therapy Clinical Trial outcomes here (updated 2023):
Michele arrived at our clinic in December 2023, living with chronic pain up to an 8/10 on the Pain Scale (at worst) for the past 11 years. She completed 10 Calmare scrambler therapy treatments, performed once daily for about 35 minutes each.)
By the end of her treatment cycle, she no longer felt pain (for the first time since 2012). She did identify feeling ‘achy,’ but this short-term feeling is to be expected after living with neuropathy for so long. We expect this feeling to dissipate during her rest and recovery period.
Due to the longevity of her nerve pain, she may eventually require a booster treatment in the event the pain should resume. But time will tell. Nonetheless, we were elevated to send this cancer warrior back to Connecticut cancer-free and pain-free for the first time in more than a decade.

Find out more about Calmare Scrambler Therapy
- Learn more about CIPN and how scrambler therapy can help to overcome this type of nerve pain: https://calmaretherapynj.com/a-better-therapy-to-treat-nerve-damage-after-chemotherapy-cipn/
- Learn more about Dr. Michael Cooney, Calmare NJ USA clinical director and global leader in the use of scrambler therapy: https://calmaretherapynj.com/about/#calmare-therapy
- If you’d like to discuss your chronic pain case with Dr. Cooney directly, complete this quick form, and the doctor will contact you within 48 hours by phone or video chat (your preference) https://calmaretherapynj.com/contact/