Several high quality scrambler therapy clinical trials have been performed by the nation’s most prestigious medical and educational institutions on the MC-5A Calmare device technology.

Click on the links below to see the scope of each study.

For an up-to-the-minute guide to all Calmare clinical trials, visit

Completed Scrambler Therapy Clinical Studies, Clinical Trials in Progress and Related News

Mayo Clinic – Chemotherapy Pain

Mayo Clinic –  CRPS

Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device (2019)

Scrambler therapy efficacy and safety for neuropathic pain correlated with chemotherapy‐induced peripheral neuropathy in adolescents

University of Wisconsin – Madison – Chemotherapy-induced Peripheral Neuropathy (CIPN)

Medscape (WebMD) reports on new cancer pain (CIPN) clinical trial outcome 

Virginia Commonwealth University School of Nursing (low back pain)

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins (PHN / Shingles)

American Society of Clinical Oncology – PHN

Massey Cancer Center at Virginia Commonwealth University – CIPN

MD Anderson Cancer Center – Scrambler Therapy to Treat Pain

Calmare Therapy – An Innovative Pain Treatment: What Is It? The Osher Center for Integrative Medicine, a collaborative partnership between Brigham and Women’s Hospital and Harvard Medical School. (Grand Rounds presentation).