Calmare Therapy® (scrambler therapy) is a non-invasive, drug-free solution for pain control and medication-resistant neuropathy.

It uses biophysical “scrambler” technology, a treatment for nerve pain that uses electrodes placed on the skin.

imageThe device works to relieve pain directly at the pain site without any reliance on medication.

Via small electrodes strategically positioned by a specially-trained doctor, a ‘no-pain’ message is transmitted directly to the nerve for a period of approximately 35 minutes per session.

Regardless of severity, pain and physical symptoms caused by the neuropathic condition can be significantly reduced-or even alleviated-by the conclusion of the 10-treatment series.

The cause of the neuropathy may be a result of injury, cancer and chemotherapy, surgery, diabetic pain, CRPS / RSD, Shingles/PHN, lower back pain, fibromyalgia (FMS), sciatic neuropathy, chronic neck pain, failed back surgery or phantom limb syndrome.

People with treatment-resistant neuropathy explain their outcomes after Calmare Therapy

For severe cases of neuropathic pain, subsequent Calmare booster treatments are sometimes, but not always, necessary for patients who have lived with the chronic pain condition for a long period of time before undergoing Calmare Therapy treatment.

Calmare is revolutionary in the treatment of severe chronic pain

  • Proven successful in the treatment of neuropathic pain by leading Calmare Technology 2012oncologic studies 
  • FDA-cleared 510(k)-cleared and European CE mark-certified
  • Pain-free
  • Non-invasive
  • Drug-free
  • No side effects

Calmare received FDA 510(k) clearance and medical device CE certification from the European Union.

History and Development

The MC-5A medical device was developed by Professor Giuseppe Marineo, a researcher and bioengineer and the founder and manager of Delta Research & Development. Delta R&D is the Bioengineering Research Center affiliated with Tor Vergata University in Rome.

Calmare Therapy – An Innovative Pain Treatment: What Is It?

Presented by the Osher Center for Integrative Medicine, a collaborative partnership between Brigham and Women’s Hospital and Harvard Medical School. (Grand Rounds presentation).

About Dr. Michael Cooney, clinical director, Calmare Therapy NJ USA 

Since 2011, Dr. Cooney has personally treated more than 1,000 patients from the U.S. and around the world suffering from a range of treatment and medication-resistant  neuropathic conditions.

He specializes in helping people battling Complex Regional Pain Syndrome (CRPS) and Reflex Sympathetic Dystrophy (RSD). 

Dr. Cooney was also one of the first doctors to successfully help patients with pain and symptoms from shingles or Postherpetic Neuropathy (PHN).

Calmare Certified Location LogoDr. Cooney is one of only seven doctors (February 2019) in the United States who has earned Certification as a Calmare provider.

He regularly acts as a consultant for new doctors and healthcare providers who are introducing scrambler therapy to their own pain management and medical practices.

Read about Calmare Therapy in Pain News Network 

How does the Calmare MC-5A device work?

Patients are comfortably connected to the Calmare Pain Therapy Treatment® device via small electrodes (similar to those used in EKG and other medical procedures) placed on the patient’s skin at the pain site/s.

The device then sends a very low current of electrical stimulation through the skin and nerve fibers, which carries a “no pain” signal to the brain, essentially overriding the previous pain signal.camare foot image with leads

In some cases, pain relief has been reported after the first treatment, but each patient’s case is unique.

During the 35-minute daily treatments over a two-week period,  the patient’s pain steadily decreases to allow the patient to resume normal daily activities and enjoy a rich quality of life that had previously been eroded by living with chronic pain.

Would you like to talk about your chronic pain condition?

Call Calmare Therapy NJ USA at (201) 933.4440 or email us at

Or fill out the information below and we’ll be happy to contact you.

(Yes, we know it’s unusual in today’s healthcare world to do this…)